No reload until gun is completely empty. No stimpacks, doctors and beds only ( I alredy use this one on any character but yeah.) Get yourself addicted to alcohool as soon as possible, think about it as dehydration.
No ammo/health bar, must check Pip-boy for HP and ammo. I made these basic rules (no explanation, I can't just put a message like this one on every single item) and I wanted opinion from other players, and suggestions I've been thinking about this for some time and I want to share some of my thoughts about how I can make a more realistic character with no mods.